Nanoparticles for antiparasitic drug delivery
Identifieur interne : 000601 ( Main/Exploration ); précédent : 000600; suivant : 000602Nanoparticles for antiparasitic drug delivery
Auteurs : Yuzhu Sun [République populaire de Chine] ; Dongmei Chen [République populaire de Chine] ; Yuanhu Pan [République populaire de Chine] ; Wei Qu [République populaire de Chine] ; Haihong Hao [République populaire de Chine] ; Xu Wang [République populaire de Chine] ; Zhenli Liu [République populaire de Chine] ; Shuyu Xie [République populaire de Chine]Source :
- Drug Delivery [ 1071-7544 ] ; 2019.
Abstract
As an emerging novel drug carrier, nanoparticles provide a promising way for effective treatment of parasitic diseases by overcoming the shortcomings of low bioavailability, poor cellular permeability, nonspecific distribution and rapid elimination of antiparasitic drugs from the body. In recent years, some kinds of ideal nanocarriers have been developed for antiparasitic drug delivery. In this review, the progress of the enhanced antiparasitic effects of different nanoparticles payload and their influencing factors were firstly summarized. Secondly, the transport and disposition process in the body were reviewed. Finally, the challenges and prospects of nanoparticles for antiparasitic drug delivery were proposed. This review will help scholars to understand the development trend of nanoparticles in the treatment of parasitic diseases and explore strategies in the development of more efficient nanocarriers to overcome the difficulty in the treatment of parasite infections in the future.
Url:
DOI: 10.1080/10717544.2019.1692968
PubMed: 31746243
PubMed Central: 6882479
Affiliations:
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Le document en format XML
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Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Qu, Wei" sort="Qu, Wei" uniqKey="Qu W" first="Wei" last="Qu">Wei Qu</name><affiliation wicri:level="1"><nlm:aff id="AF0001"><institution>National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues</institution>, Wuhan,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hao, Haihong" sort="Hao, Haihong" uniqKey="Hao H" first="Haihong" last="Hao">Haihong Hao</name><affiliation wicri:level="1"><nlm:aff id="AF0001"><institution>National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues</institution>, Wuhan,<country>China</country>;</nlm:aff><country xml:lang="fr">République 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Yuzhu" uniqKey="Sun Y" first="Yuzhu" last="Sun">Yuzhu Sun</name><affiliation wicri:level="1"><nlm:aff id="AF0001"><institution>National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues</institution>, Wuhan,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Chen, Dongmei" sort="Chen, Dongmei" uniqKey="Chen D" first="Dongmei" last="Chen">Dongmei Chen</name><affiliation wicri:level="1"><nlm:aff id="AF0001"><institution>National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues</institution>, Wuhan,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="AF0002"><institution>MOA Laboratory for Risk Assessment of Quality and Safety of Livestock and Poultry Products, Huazhong Agricultural University</institution>, Wuhan,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Pan, Yuanhu" sort="Pan, Yuanhu" uniqKey="Pan Y" first="Yuanhu" last="Pan">Yuanhu Pan</name><affiliation wicri:level="1"><nlm:aff id="AF0001"><institution>National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues</institution>, Wuhan,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Qu, Wei" sort="Qu, Wei" uniqKey="Qu W" first="Wei" last="Qu">Wei Qu</name><affiliation wicri:level="1"><nlm:aff id="AF0001"><institution>National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues</institution>, Wuhan,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hao, Haihong" sort="Hao, Haihong" uniqKey="Hao H" first="Haihong" last="Hao">Haihong Hao</name><affiliation wicri:level="1"><nlm:aff id="AF0001"><institution>National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues</institution>, Wuhan,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Xu" sort="Wang, Xu" uniqKey="Wang X" first="Xu" last="Wang">Xu Wang</name><affiliation wicri:level="1"><nlm:aff id="AF0001"><institution>National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues</institution>, Wuhan,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Zhenli" sort="Liu, Zhenli" uniqKey="Liu Z" first="Zhenli" last="Liu">Zhenli Liu</name><affiliation wicri:level="1"><nlm:aff id="AF0001"><institution>National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues</institution>, Wuhan,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Xie, Shuyu" sort="Xie, Shuyu" uniqKey="Xie S" first="Shuyu" last="Xie">Shuyu Xie</name><affiliation wicri:level="1"><nlm:aff id="AF0001"><institution>National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues</institution>, Wuhan,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Drug Delivery</title><idno type="ISSN">1071-7544</idno><idno type="eISSN">1521-0464</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Abstract</title><p>As an emerging novel drug carrier, nanoparticles provide a promising way for effective treatment of parasitic diseases by overcoming the shortcomings of low bioavailability, poor cellular permeability, nonspecific distribution and rapid elimination of antiparasitic drugs from the body. In recent years, some kinds of ideal nanocarriers have been developed for antiparasitic drug delivery. In this review, the progress of the enhanced antiparasitic effects of different nanoparticles payload and their influencing factors were firstly summarized. Secondly, the transport and disposition process in the body were reviewed. Finally, the challenges and prospects of nanoparticles for antiparasitic drug delivery were proposed. This review will help scholars to understand the development trend of nanoparticles in the treatment of parasitic diseases and explore strategies in the development of more efficient nanocarriers to overcome the difficulty in the treatment of parasite infections in the future.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Abamor, Es" uniqKey="Abamor E">ES Abamor</name></author><author><name sortKey="Tosyali, Oa" uniqKey="Tosyali O">OA Tosyali</name></author><author><name sortKey="Bagirova, M" uniqKey="Bagirova M">M Bagirova</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aditya, Np" uniqKey="Aditya N">NP Aditya</name></author><author><name sortKey="Chimote, G" uniqKey="Chimote G">G Chimote</name></author><author><name sortKey="Gunalan, K" uniqKey="Gunalan K">K Gunalan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Afonso, A" uniqKey="Afonso A">A 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Niu</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Sun, Yuzhu" sort="Sun, Yuzhu" uniqKey="Sun Y" first="Yuzhu" last="Sun">Yuzhu Sun</name></noRegion><name sortKey="Chen, Dongmei" sort="Chen, Dongmei" uniqKey="Chen D" first="Dongmei" last="Chen">Dongmei Chen</name><name sortKey="Chen, Dongmei" sort="Chen, Dongmei" uniqKey="Chen D" first="Dongmei" last="Chen">Dongmei Chen</name><name sortKey="Hao, Haihong" sort="Hao, Haihong" uniqKey="Hao H" first="Haihong" last="Hao">Haihong Hao</name><name sortKey="Liu, Zhenli" sort="Liu, Zhenli" uniqKey="Liu Z" first="Zhenli" last="Liu">Zhenli Liu</name><name sortKey="Pan, Yuanhu" sort="Pan, Yuanhu" uniqKey="Pan Y" first="Yuanhu" last="Pan">Yuanhu Pan</name><name sortKey="Qu, Wei" sort="Qu, Wei" uniqKey="Qu W" first="Wei" last="Qu">Wei Qu</name><name sortKey="Wang, Xu" sort="Wang, Xu" uniqKey="Wang X" first="Xu" last="Wang">Xu Wang</name><name sortKey="Xie, Shuyu" sort="Xie, Shuyu" uniqKey="Xie S" first="Shuyu" last="Xie">Shuyu Xie</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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